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A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks
Journal article   Peer reviewed

A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks

Ratima Suntornnond, Edgar Yong Sheng Tan, Jia An and Chee Kai Chua
Materials, Vol.9(9), pp.756-756
06/09/2016
PMID: 28773879

Abstract

Chemistry Chemistry, Physical Materials Science Materials Science, Multidisciplinary Metallurgy & Metallurgical Engineering Physical Sciences Physics Physics, Applied Physics, Condensed Matter Science & Technology Technology
Pneumatic extrusion-based bioprinting is a recent and interesting technology that is very useful for biomedical applications. However, many process parameters in the bioprinter need to be fully understood in order to print at an adequate resolution. In this paper, a simple yet accurate mathematical model to predict the printed width of a continuous hydrogel line is proposed, in which the resolution is expressed as a function of nozzle size, pressure, and printing speed. A thermo-responsive hydrogel, pluronic F127, is used to validate the model predictions. This model could provide a platform for future correlation studies on pneumatic extrusion-based bioprinting as well as for developing new bioink formulations.
url
https://doi.org/10.3390/ma9090756View
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