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A novel single-layered MoS2 nanosheet based microfluidic biosensor for ultrasensitive detection of DNA
Journal article   Peer reviewed

A novel single-layered MoS2 nanosheet based microfluidic biosensor for ultrasensitive detection of DNA

Yinxi Huang, Yumeng Shi, Hui Ying Yang and Ye Ai
Nanoscale, Vol.7(6), pp.2245-2249
14/02/2015
DOI: https://doi.org/10.1039/c4nr07162j
PMID: 25567642

Abstract

Biosensing Techniques Dimethylpolysiloxanes - chemistry DNA - chemistry DNA, Single-Stranded Fluorescent Dyes - chemistry Materials Testing Microfluidics - instrumentation Microfluidics - methods Microscopy, Atomic Force Nanoparticles - chemistry Nanostructures Nanotechnology - methods Optics and Photonics Reproducibility of Results Sensitivity and Specificity Solutions Spectrometry, Fluorescence Surface Properties
Recently, MoS2 nanosheets were demonstrated to be able to spontaneously adsorb single-stranded DNA, acting as efficient dye quenchers. We herein report a novel microfluidic biosensor for fluorescent DNA detection based on single-layered MoS2 nanosheets. The proposed platform is simple, rapid and visible with high sensitivity and selectivity.

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