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Bridging the academia-to-industry gap: organ-on-a-chip platforms for safety and toxicology assessment
Journal article   Peer reviewed

Bridging the academia-to-industry gap: organ-on-a-chip platforms for safety and toxicology assessment

Terry Ching, Yi-Chin Toh, Michinao Hashimoto and Yu Shrike Zhang
Trends in pharmacological sciences (Regular ed.), Vol.42(9), pp.715-728
01/09/2021
PMID: 34187693

Abstract

Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology
Some organ-on-a-chip (OoC) systems for drug evaluation show better predictive capabilities than planar, static cell cultures and animal models. One of the ongoing initiatives led by OoC developers is to bridge the academia-to-industry gap in the hope of gaining wider adoption by end-users - academic biological researchers and industry. We discuss several recommendations that can help to drive the adoption of OoC systems by the market. We first review some key challenges faced by OoC developers before highlighting current advances in OoC platforms. We then offer recommendations for OoC developers to promote the uptake of OoC systems by the industry.
url
https://doi.org/10.1016/j.tips.2021.05.007View
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