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Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial
Journal article   Peer reviewed

Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial

Julio Rosenstock, Vlado Perkovic, Odd Erik Johansen, Mark E. Cooper, Steven E. Kahn, Nikolaus Marx, John H. Alexander, Michael Pencina, Robert D. Toto, Christoph Wanner, …
JAMA : the journal of the American Medical Association, Vol.321(1), pp.69-79
01/01/2019
PMID: 30418475

Abstract

Online First Original Investigation
This randomized clinical trial compares the effects of the dipeptidyl peptidase 4 inhibitor linagliptin vs placebo plus usual care on cardiovascular (CV) and renal outcomes in adults with type 2 diabetes and high CV and renal risk.
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https://doi.org/10.1001/jama.2018.18269View
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