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Portable resistive pulse-activated lens-free cell imaging system
Journal article   Peer reviewed

Portable resistive pulse-activated lens-free cell imaging system

Jinhong Guo, Xiwei Huang, Dongyuan Shi, Hao Yu, Ye Ai, Chang Ming Li and Yuejun Kang
RSC advances, Vol.4(99), pp.56342-56345
01/01/2014

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
We demonstrate a portable lens-free cell imaging system activated by resistive pulses that are induced by biological cells in a microfluidic channel. This imaging on-chip flow cytometer integrates CMOS with microfluidics as a standalone on-chip analytical device. The preliminary version of this system is able to provide dual-parametric study ( light contrast image and modulated electrical pulse) for each biological cell. Red blood cells and a tumor cell line (HepG2) are used to demonstrate the performance of this chip for flow analysis of biological samples.

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