Abstract
An RC-to-time constant interface circuit was implemented in 0. 18 mu m CMOS to characterise the conductive polymer labelled deoxyribonucleic acid (DNA) hybridisation activity on nano-sensor micro-arrays. Measured results show that sub-picomolar DNA (0.1-10 pM) are able to be differentiated with respect to their electrical parameters of 1-23 G Omega resistances parallel with 2.8 down to 0. 1 nF capacitances.